Abstract Background Natural killer (NK) cells are an important resource of the innate immune system directly involved in the spontaneous recognition and lysis of virus-infected and tumor cells.An exquisite balance of inhibitory and activating receptors tightly controls the NK cell activity.At present, one of the best-characterized activating recept
Studying the factors leading to a pathological change in the cardiac structure in patients with rheumatoid arthritis (RA) can contribute to improvement in early diagnosis and to prevention of premature mortality from cardiovascular events.Objective.To study the types of left ventricular (LV) remodeling in patients with RA, by taking into account tr
This paper introduces two variants of a multiple criteria scatter search to deal with nonlinear continuous and combinatorial problems, applying a tabu search approach as a diversification generator method.Frequency memory and another escape mechanism are used to diversify the search.A Pareto relation is applied in order to designate a subset of the
Bayesian techniques for engineering problems, which rely on Gaussian Nail Top Coat process (GP) regression, are known for their ability to quantify epistemic and aleatory uncertainties and for being data efficient.The mathematical elegance of applying these methods usually comes at a high computational cost when compared to deterministic and empiri
Background: Magnetic resonance spectroscopy (MRS) has been used to identify gamma-aminobutyric acid (GABA) alterations Honeycomb Garlands in mood disorders, particularly in the medial prefrontal cortex (mPFC) where decreased concentrations have been associated with anhedonia.In major depressive disorder (MDD), prior work suggests that repetitive tr